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Revlimid Therapy May Delay Myeloma Progression and Increase Survival

Revlimid (lenalidomide) therapy maintenance has been shown to delay disease progression and extend survival in newly diagnosed multiple myeloma (NDMM) patients who receive a transplant of their own blood-forming stem cells, called autologous...

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STRO-001 Eliminates or Slows Growth of Myeloma and Lymphoma in...

Sutro Biopharma's STRO-001 eliminates or significantly slows the growth of non-Hodgkin lymphoma and multiple myeloma tumors, studies in mice indicate. Sutro expects the results to support its investigational new drug application for STRO-001. The U.S. Federal Drug Administration must approve the...

Learn more about a study supporting the use of VAX-DC cell therapy, a transplant of immune cells that improves the anti-tumor response of MM patients. Tax Deductions, Forex Trading, Gaming, Science, Videos, Videogames, Game

VAX-DC/MM Cell Therapy Shows Promise in Relapsed or Refractory...

NantKwest’s Vax-DC/MM cell therapy has induced a partial or complete response in 42 percent of relapsed or refractory multiple myeloma (MM) and lymphoma patients in a Phase 1 clinical trial (NCT02248402). The findings showed no evidence of severe adverse events. Results of this work were...

Twenty-four people in a Phase 1 clinical trial focusing on psoriasis have received a therapy that is also being developed for multiple sclerosis. Multiple Sclerosis, Medical Advice, Trials, Clinic, Therapy, How To Plan, News Today, Ms, Science

Myeloma Patients Who Receive the Maintenance Therapy Revlimid Live...

Newly diagnosed multiple myeloma patients who use Revlimid (lenalidomide) as a maintenance therapy after a stem cell transplant live significantly longer than those receiving a placebo or nothing, a meta-analysis shows. The research deals with autologous stem cells, or those taken from a...

Johnson & Johnson’s Erleada (apalutamide) is the first FDA-approved therapy for non-metastatic, castration-resistant prostate cancer. Ulcerative Colitis, Autoimmune Disease, Crohn's Disease, Prostate Cancer, Breast Cancer, Social Security Benefits, The Motley Fool, Cystic Fibrosis, Health Insurance Plans

Cellectar’s CLR 131 Shows Early Promising Survival Outcomes in...

Myeloma patients who received a single dose of the investigational therapy CLR 131 in an ongoing Phase 1 clinical trial have reached a median overall survival of 22 months, according to the drug's developer, Cellectar Biosciences. Cellectar is a clinical stage biotech developing...

Read about how a suggestion that minimal residual disease measurements be used as a surrogate marker in myeloma clinical trials met with skepticism. Clinic, Chef Jackets, Coat, Disability, Sample Resume, Minimal, Science, Recipe, News

Minimal Residual Disease in Myeloma Suggested as Clinical Trial...

Minimal residual disease, a measurement that shows a low level of disease detected, should be used as an endpoint in myeloma clinical trials, a study exploring previously published data suggests. The study, “Association of Minimal Residual Disease With Superior Survival Outcomes in Patients With...

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Excess Body Fat Increases Risk for 8 More Cancer Types, Special...

The association between excess body fat and increased risk of various cancers is an undisputed fact. Now, the findings of a working group from the International Agency for Research on Cancer (IARC) adds eight additional types to the list of cancers whose risks are increased by being overweight...

Read about how adding Darzalex to the treatment of relapsing or refractory multiple myeloma with Velcade and Decadron improved progression-free survival. Relapse, Clinic, Things To Do, Playing Cards, How Are You Feeling, Feelings, Work Hard, Journals, Articles

Myeloma Patients on Darzalex Combination Treatment Fared Better in...

Adding Darzalex (daratumumab) to the treatment of multiple myeloma with Velcade (bortezomib) and dexamethasone significantly improved progression-free survival in a clinical trial of patients who had relapsed or did not respond to standard treatment. The study, “Daratumumab, Bortezomib, and...

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Autoimmune Hemolytic Anemia in Sarcoidosis Patient Successfully...

Patients with sarcoidosis may develop a condition known as autoimmune hemolytic anemia, in which the red blood cells are prematurely destroyed by the immune system. Although this is not well documented, researchers at Warwick Hospital in England have reported the case of a patient who exhibited...

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Bacterial Composition Seen to Differ in Respiratory Tract of...

There is a difference in the composition of microorganisms in the respiratory tract of people with sarcoidosis and that of healthy individuals according to a study conducted by Polish scientists. The authors of the study suggest that this may be a factor contributing to an increased colonization...

Learn about polymorphonuclear leukocytes, or PMNs, white blood cells linked to your risk of infection, allergies and other illnesses. Antigen Presenting Cell, Blood Test Results, Filter, Cell Line, Multiple Myeloma, T Cell, White Blood Cells, Fungal Infection

Relapsed, Refractory Multiple Myeloma Progression Free Survival...

Elotuzumab in combination with bortezomib and dexamethasone prolongs the progression free survival of patients with relapsed or refractory multiple myeloma (RRMM), according to the study “Randomized phase 2 study of elotuzumab plus bortezomib/dexamethasone (Bd) versus Bd for relapsed/refractory...

Learn about polymorphonuclear leukocytes, or PMNs, white blood cells linked to your risk of infection, allergies and other illnesses. Antigen Presenting Cell, Blood Test Results, Filter, Cell Line, Multiple Myeloma, T Cell, White Blood Cells, Fungal Infection

Myeloma Development Might Be Stalled by Blocking Pathway from a...

Researchers at the University of Birmingham have found that blocking a specific mechanism in the benign condition monoclonal gammophaty of undetermined significance (MGUS) may prevent the development of multiple myeloma. The findings were published in the journal Leukemia in the study...

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Multiple Myeloma Treatment Outcomes May Improve with...

A recent review article, “The Role of Intracellular Signaling Pathways in the Pathogenesis of Multiple Myeloma and Novel Therapeutic Approaches” published in the Journal of Clinical and Experimental Hematopathology, pooled the most promising new "next generation" drug candidate that are being...

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EU OKs Extended Indication for Amgen’s Myeloma Drug Kyprolis

Global biotech firm Amgen has announced that the European Commission (EC) approved a variation to the marketing authorization for Kyprolis (carfilzomib) to be used in combination with dexamethasone alone for adults suffering from multiple myeloma who have been treated at least once. This...

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Risk of Myeloma Still Small Despite Newly Revealed Gene Mutations

In the largest study to date, researchers from The Institute of Cancer Research in London identified eight new gene mutations increasing the risk of developing myeloma — a risk that is still very small, according to experts. The study...

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Risk of Myeloma Still Small Despite Newly Revealed Gene Mutations

In the largest study to date, researchers from The Institute of Cancer Research in London identified eight new gene mutations increasing the risk of developing myeloma — a risk that is still very small, according to experts. The study...